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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCYL3 All Species: 16.97
Human Site: S612 Identified Species: 31.11
UniProt: Q8IZE3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZE3 NP_065156.5 742 82857 S612 L L S L T E E S M P W K S S L
Chimpanzee Pan troglodytes XP_513987 742 82925 S612 L L S L T E E S M P W K S S L
Rhesus Macaque Macaca mulatta XP_001096051 736 82375 S612 L L P L T E E S M P W K S S L
Dog Lupus familis XP_537198 743 82483 S612 L L S L T E E S R P L K S S P
Cat Felis silvestris
Mouse Mus musculus Q9DBQ7 735 81315 K611 V P L T E E S K P L Q S S P S
Rat Rattus norvegicus Q5M9F8 807 89107 V659 L E Q E A E S V L A Q Q D D W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514536 1518 163635 S1269 V A A V L A D S V R F K K I R
Chicken Gallus gallus NP_001012613 698 77220 E591 V L P K Q T L E E R L K S S L
Frog Xenopus laevis Q561M0 827 91284 A707 D G W G W D D A F P T V P P A
Zebra Danio Brachydanio rerio NP_955951 768 85305 S631 R L N P S M K S A P D H N H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610175 683 77833 N578 S Y R T G K C N L S V G V N E
Honey Bee Apis mellifera XP_001123124 613 70111 Q509 Q P S K K I S Q S Q S K S N D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177952 810 89574 L663 L K G T G K P L K L K D M V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.1 85.5 N.A. 80.7 21.9 N.A. 31.8 61.9 21.8 51.9 N.A. 25.7 28.4 N.A. 33.5
Protein Similarity: 100 99.1 96.7 90.3 N.A. 87.7 38.5 N.A. 37.4 71.5 39 67.5 N.A. 45.9 49.7 N.A. 50.7
P-Site Identity: 100 100 93.3 80 N.A. 13.3 13.3 N.A. 13.3 33.3 6.6 20 N.A. 0 20 N.A. 6.6
P-Site Similarity: 100 100 93.3 80 N.A. 20 26.6 N.A. 53.3 40 26.6 46.6 N.A. 26.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 8 0 8 8 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 16 0 0 0 8 8 8 8 8 % D
% Glu: 0 8 0 8 8 47 31 8 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 8 8 8 16 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 8 0 16 8 16 8 8 8 0 8 54 8 0 0 % K
% Leu: 47 47 8 31 8 0 8 8 16 16 16 0 0 0 31 % L
% Met: 0 0 0 0 0 8 0 0 24 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 0 0 0 0 8 16 0 % N
% Pro: 0 16 16 8 0 0 8 0 8 47 0 0 8 16 16 % P
% Gln: 8 0 8 0 8 0 0 8 0 8 16 8 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 0 8 16 0 0 0 0 8 % R
% Ser: 8 0 31 0 8 0 24 47 8 8 8 8 54 39 8 % S
% Thr: 0 0 0 24 31 8 0 0 0 0 8 0 0 0 8 % T
% Val: 24 0 0 8 0 0 0 8 8 0 8 8 8 8 0 % V
% Trp: 0 0 8 0 8 0 0 0 0 0 24 0 0 0 8 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _